SEXUAL WELLNESS
PT-141 / Oxytocin
$240/30 strips ($8/dose)
Our PT-141/Oxytocin dissolvable strips are formulated to support improved desire, heightened sensitivity, and more consistent arousal. With rapid absorption and an effortless format, they help women feel more confident, more responsive, and more in control of their sexual wellness.
Starting at 8 dollars/dose
Works on the brain — not the vascular system
Designed specifically for women
Effects can last up to 24 hours
Prescription required — licensed provider review included with every order
What is PT-141 / Oxytocin?
PT-141 (Bremelanotide) and Oxytocin work synergistically to address the full spectrum of female sexual dysfunction. PT-141 activates melanocortin receptors in the hypothalamus to enhance sexual desire, while Oxytocin — often called the "bonding hormone" — amplifies emotional intimacy, trust, and physical sensitivity. This combination is specifically designed for women because female sexual response is uniquely tied to both neurological desire AND emotional connection, unlike male sexual dysfunction which is primarily vascular. Together they target the brain and the heart — not the vascular system — making this protocol ideal for women whose sexual concerns involve desire, arousal, satisfaction, and emotional intimacy.
Enhances sexual desire and arousal
Strengthens emotional intimacy and bonding
Specifically designed for women's sexual response
Works on the brain — not the vascular system
Effects can last up to 24 hours
No negative cardiac interactions
The Science Behind PT-141 / Oxytocin
PT-141 activates MC3R and MC4R receptors in the brain's hypothalamus, triggering dopamine release in regions associated with sexual motivation. Oxytocin acts on the limbic system and peripheral tissues, enhancing tactile sensitivity, promoting relaxation, and strengthening emotional bonding. The combination addresses the dual nature of female sexual response — neurological desire (PT-141) and emotional/physical intimacy (Oxytocin). Effects begin within 45–60 minutes and can last 8–12 hours.
Clinical Evidence
Multiple clinical trials of Bremelanotide demonstrate significant improvements in desire, satisfaction, and frequency of sexual activity in women with hypoactive sexual desire disorder (HSDD). Oxytocin research shows it enhances pair-bonding, trust, and sexual satisfaction, with studies indicating increased physiological arousal and orgasmic intensity in women.
Medical Disclaimer: This information is for educational purposes. Individual results vary. All treatments require a prescription from a licensed provider who will evaluate your medical history before approving any protocol.
Who Is PT-141 / Oxytocin For?
Women experiencing low libido, hypoactive sexual desire disorder (HSDD), difficulty with arousal or orgasm, or sexual dissatisfaction related to stress, hormonal changes, or emotional disconnect. Especially beneficial for women who cannot use vasodilatory medications or whose sexual concerns involve both desire and intimacy.
Dosage & Administration
Administered as a sublingual film 45–60 minutes before sexual activity. Place the film under the tongue and allow it to dissolve completely. Your provider will determine your individualized dosing protocol. Should not be used more than once in 24 hours or more than 8 times per month.
Personalized Dosing Plan
Your dose is titrated specifically for your body and goals by your provider based on your intake assessment.
All Supplies Included
Everything you need is shipped directly to your door, including the medication and full administration instructions.
On-Demand Timeline
A typical progression following a single administration of PT-141 / Oxytocin.
Initial Activation
0–2 HoursFollowing administration, PT-141 begins binding to melanocortin receptors in the brain while Oxytocin starts acting on the limbic system. Women may notice a gentle warming sensation, mild facial flushing, and the first stirrings of emotional openness as desire and bonding pathways are activated.
Peak Desire & Intimacy
2–4 HoursThis is typically the window of peak efficacy. Women report a significant increase in spontaneous sexual desire, heightened tactile sensitivity, and a deeper sense of emotional connection and trust — the combined effect of neurological arousal (PT-141) and the bonding hormone (Oxytocin).
Sustained Connection
12–24 HoursUnlike traditional medications that wear off quickly, the combination remains active in the system. Enhanced libido, physical responsiveness, and lingering feelings of emotional intimacy and closeness often continue strongly throughout the first full day.
Prolonged Window
Up to 72 HoursThe effects gradually taper off, but many women report lingering benefits — increased sensual vitality, strengthened emotional bonds, and an overall enhanced sense of sexual wellbeing for up to three days after a single dose.
Do I qualify?
This treatment involves receiving compounded PT-141 (Bremelanotide) and Oxytocin combination therapy delivered as a sublingual film. The goal is to treat hypoactive sexual desire disorder and improve sexual arousal, emotional intimacy, and physical sensitivity through central nervous system pathways — specifically designed for the dual nature of women's sexual response.
Benefits may include enhanced sexual desire, arousal, emotional bonding, and tactile sensitivity. Common risks include nausea (which can be significant and last for several hours), flushing, headache, and temporary increases in blood pressure and decrease in heart rate.
This treatment is elective. Alternatives include counseling, lifestyle modifications, or other therapies for sexual dysfunction.
Assessment Requirements
- Must be 18 years of age or older
- Must complete a full medical intake and wellness assessment
- Must not have any of the contraindications listed below
Who Is Not a Good Candidate for PT-141 / Oxytocin Therapy?
For your safety, PT-141 / Oxytocin therapy is contraindicated if you have any of the following conditions or circumstances:
Your partner in longevity and healthspan.
Treatments
All Treatments
© 2026 toniRx. All rights reserved.
The quizzes made available on the TONIRX website do not create a doctor-patient relationship between the individual completing the assessment and TONIRX.
Our network of US-licensed doctors adhere to rigorous medical protocols designed for patient safety and they have established exclusionary criteria to determine if an individual does not qualify for treatment. The answers an individual provides to the TONIRX quiz consequently determine if the individual is screened out of eligibility for medication. A US-licensed clinician will meet with an individual after checkout to determine if they qualify for a prescription.
Clinicians retain the decision to prescribe compounded medications to patients.
All claims and benefits on this website refer to self-reported data from customers on a treatment plan that includes compounded medications and consultations with medical professionals. Results from compounded medications found on the TONIRX platform may vary and be affected by an individual's adherence to the program and their clinician's recommendations. Compounded medications are produced in FDA-regulated facilities. Although these facilities are highly regulated, the medications are not FDA-approved or evaluated for safety, efficacy, or quality. The decision to use compounded drugs is guided by the licensed provider's medical judgment, which is informed by a telehealth consultation and medical history.
We encourage all prospective users of compounded medications to speak with their provider about the specific risks and benefits that may come with the use of compounded medication. TONIRX does not produce compounded medications, and individuals may receive medication that looks different than what is portrayed on the website.
Pharmacy Providers
We are partnered with multiple USA certified pharmacies to bring the best product and overall experience to our members. Our team meets regularly with pharmacies to discuss any product shortages, shipping delays, and get updated reports on their medication testing.
Results vary based on starting weight, overall health, and program adherence. Results may vary. Medication prescriptions are at the discretion of medical providers and may not be suitable for everyone. Consult a healthcare professional before using medication or starting any weight loss program.
Data, photos, claims and other information may be associated with results derived from clinical trials, studies or public information and may not be representative of TONIRX member experience.
Certain materials on this website, including text, images, and other media, may be generated or enhanced using artificial intelligence technologies. No representation or warranty is made regarding the accuracy, completeness, or reliability of such content. Individuals appearing in advertisements may be actors or models.
Testimonials on the website are from TONIRX patients. For patient privacy, images representing those testimonials may use models.
By accepting our Terms of Use, you additionally understand and agree that TONIRX is not acting as a pharmacy, nor does TONIRX control or interfere with any such services. By accepting these Terms of Use, you understand and agree that you may be entering into a relationship with a pharmacy, pharmacist, and/or pharmacy group or other such relationship with any one or more such third-party entities.
Available in all 50 states,
Your partner in longevity and healthspan extension.
Science-backed treatments delivered to your door.
Treatments
All Treatments
© 2026 toniRx. All rights reserved.
The quizzes made available on the TONIRX website do not create a doctor-patient relationship between the individual completing the assessment and TONIRX.
Our network of US-licensed doctors adhere to rigorous medical protocols designed for patient safety and they have established exclusionary criteria to determine if an individual does not qualify for treatment. The answers an individual provides to the TONIRX quiz consequently determine if the individual is screened out of eligibility for medication. A US-licensed clinician will meet with an individual after checkout to determine if they qualify for a prescription.
Clinicians retain the decision to prescribe compounded medications to patients.
All claims and benefits on this website refer to self-reported data from customers on a treatment plan that includes compounded medications and consultations with medical professionals. Results from compounded medications found on the TONIRX platform may vary and be affected by an individual's adherence to the program and their clinician's recommendations. Compounded medications are produced in FDA-regulated facilities. Although these facilities are highly regulated, the medications are not FDA-approved or evaluated for safety, efficacy, or quality. The decision to use compounded drugs is guided by the licensed provider's medical judgment, which is informed by a telehealth consultation and medical history.
We encourage all prospective users of compounded medications to speak with their provider about the specific risks and benefits that may come with the use of compounded medication. TONIRX does not produce compounded medications, and individuals may receive medication that looks different than what is portrayed on the website.
Pharmacy Providers
We are partnered with multiple USA certified pharmacies to bring the best product and overall experience to our members. Our team meets regularly with pharmacies to discuss any product shortages, shipping delays, and get updated reports on their medication testing.
Results vary based on starting weight, overall health, and program adherence. Results may vary. Medication prescriptions are at the discretion of medical providers and may not be suitable for everyone. Consult a healthcare professional before using medication or starting any weight loss program.
Data, photos, claims and other information may be associated with results derived from clinical trials, studies or public information and may not be representative of TONIRX member experience.
Certain materials on this website, including text, images, and other media, may be generated or enhanced using artificial intelligence technologies. No representation or warranty is made regarding the accuracy, completeness, or reliability of such content. Individuals appearing in advertisements may be actors or models.
Testimonials on the website are from TONIRX patients. For patient privacy, images representing those testimonials may use models.
By accepting our Terms of Use, you additionally understand and agree that TONIRX is not acting as a pharmacy, nor does TONIRX control or interfere with any such services. By accepting these Terms of Use, you understand and agree that you may be entering into a relationship with a pharmacy, pharmacist, and/or pharmacy group or other such relationship with any one or more such third-party entities.
Available in all 50 states,